Current status of islet xenotransplantation
نویسندگان
چکیده
منابع مشابه
Current status of xenotransplantation.
Correction Contact me if this article is corrected. Citations Contact me when this article is cited. Topic collections Contact me when new articles are published in these topic areas. Intervention Other; Gastroenterology; Liver/ Biliary Tract/ Pancreatic Diseases; Cardiovascular Transplantation; Kidney Transplantation; Liver Transplantation; Transplantation, Cardiothoracic Surgery; Endocrine Su...
متن کاملPig-Islet Xenotransplantation: Recent Progress and Current Perspectives
Islet xenotransplantation is one prospective treatment to bridge the gap between available human cells and needs of patients with diabetes. Pig represents an ideal candidate for obtaining such available cells. However, potential clinical application of pig islet still faces obstacles including inadequate yield of high-quality functional islets and xenorejection of the transplants. Adequate amou...
متن کاملClinical Islet Xenotransplantation
Type 1 diabetes (T1D) is a major health problem throughout the world. In the U.S., it is estimated that about 1.5 million people suffer from T1D. Even when well controlled—by frequent monitoring of blood glucose and administration of insulin, the long-term complications of the disease are significant and include cardiovascular disease, nephropathy, retinopathy, and neuropathy (1). Here we revie...
متن کاملPiscine islet xenotransplantation.
Tilapia, a teleost fish species with large anatomically discrete islet organs (Brockmann bodies; BBs) that can be easily harvested without expensive and fickle islet isolation procedures, make an excellent donor species for experimental islet xenotransplantation research. When transplanted into streptozotocin-diabetic nude or severe combined immunodeficient mice, BBs provide long-term normoglyc...
متن کاملCurrent status of clinical islet transplantation.
Islet transplantation is currently being explored as a treatment for patients with type 1 diabetes. At present, the number of patients becoming insulin-independent is rapidly increasing world-wide applying the transplantation protocol originally described by the group in Edmonton. A hallmark in this procedure is repeated infusions of islets obtained from 2 to 4 donors until normoglycemia is ach...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Surgery
سال: 2015
ISSN: 1743-9191
DOI: 10.1016/j.ijsu.2015.07.703